diff --git a/.github/workflows/ci.yml b/.github/workflows/ci.yml
index f5ca8b7325f..6b918c3bb37 100644
--- a/.github/workflows/ci.yml
+++ b/.github/workflows/ci.yml
@@ -68,6 +68,24 @@ jobs:
           # https://docs.github.com/en/actions/security-guides/automatic-token-authentication#about-the-github_token-secret
           token: ${{secrets.GITHUB_TOKEN}}
 
+  screen-reader-windows:
+    name: Screen Reader (Windows / NVDA)
+    runs-on: windows-2025
+    timeout-minutes: 15
+    permissions:
+      contents: read
+    steps:
+      - uses: actions/checkout@de0fac2e4500dabe0009e67214ff5f5447ce83dd # v6.0.2
+      - name: Set up pnpm
+        uses: pnpm/action-setup@8912a9102ac27614460f54aedde9e1e7f9aec20d # v6.0.5
+      - name: Use Node.js 22.x
+        uses: actions/setup-node@48b55a011bda9f5d6aeb4c2d9c7362e8dae4041e # v6.4.0
+        with:
+          node-version: '22.23.2'
+          cache: 'pnpm'
+      - run: pnpm install
+      - run: pnpm test:screen-reader
+
   # Mirrors the real publish workflow environment (`publish.yml`) so an env
   # mismatch — e.g. the Node version pinned by `publish-prepare` violating our
   # engineStrict `engines` range — is caught here instead of during publishing.
diff --git a/package.json b/package.json
index 5a5459e2f15..5313e44c735 100644
--- a/package.json
+++ b/package.json
@@ -45,6 +45,9 @@
     "test:regressions:dev": "vite --config test/regressions/vite.config.mjs --port 5173",
     "test:regressions:run": "cross-env VITEST_ENV=chromium vitest run --project regressions",
     "test:regressions:server": "serve test/regressions -p 5173",
+    "pretest:screen-reader": "guidepup install",
+    "test:screen-reader": "playwright test --config test/screen-reader/playwright.config.ts",
+    "test:screen-reader:setup": "guidepup setup",
     "test:_unit": "cross-env TZ=UTC vitest --project @base-ui/react --project @base-ui/utils --project docs",
     "test:jsdom": "cross-env VITEST_ENV=jsdom pnpm test:_unit",
     "test:jsdom:coverage": "pnpm test:jsdom --coverage",
@@ -66,6 +69,9 @@
     "@arethetypeswrong/cli": "0.18.5",
     "@babel/plugin-transform-react-constant-elements": "7.29.7",
     "@base-ui/monorepo-tests": "workspace:*",
+    "@guidepup/guidepup": "0.33.1",
+    "@guidepup/playwright": "0.19.1",
+    "@guidepup/setup": "0.24.6",
     "@microsoft/api-extractor": "7.58.12",
     "@mui/internal-code-infra": "0.0.4-canary.101",
     "@mui/internal-netlify-cache": "0.0.3-canary.5",
diff --git a/pnpm-lock.yaml b/pnpm-lock.yaml
index 5d9d8c69aa8..d5df1aa7cd5 100644
--- a/pnpm-lock.yaml
+++ b/pnpm-lock.yaml
@@ -5,6 +5,7 @@ settings:
   excludeLinksFromLockfile: false
 
 overrides:
+  '@guidepup/setup>@guidepup/record': '-'
   brace-expansion@1: 1.1.18
   brace-expansion@2: 2.1.4
   brace-expansion@5: 5.0.9
@@ -34,12 +35,21 @@ importers:
       '@base-ui/monorepo-tests':
         specifier: workspace:*
         version: link:test
+      '@guidepup/guidepup':
+        specifier: 0.33.1
+        version: 0.33.1
+      '@guidepup/playwright':
+        specifier: 0.19.1
+        version: 0.19.1(@guidepup/guidepup@0.33.1)(@playwright/test@1.62.1)
+      '@guidepup/setup':
+        specifier: 0.24.6
+        version: 0.24.6
       '@microsoft/api-extractor':
         specifier: 7.58.12
         version: 7.58.12(@types/node@22.20.1)
       '@mui/internal-code-infra':
         specifier: 0.0.4-canary.101
-        version: 0.0.4-canary.101(4c6243aed1f3c8d993ccce0bc6817d78)
+        version: 0.0.4-canary.101(4dd64b75bdb2e090bf30a93c72a30a32)
       '@mui/internal-netlify-cache':
         specifier: 0.0.3-canary.5
         version: 0.0.3-canary.5
@@ -1613,6 +1623,19 @@ packages:
     resolution: {integrity: sha512-GmzA9ckNokPypTg10pgpeHNQe7ph+iIKKmhKu3Ob9ANkswreCx7R3cKmY781K8QK3AqVL3xVh9A42JvIAbkkSA==}
     engines: {node: ^20.17.0 || >=22.9.0}
 
+  '@guidepup/guidepup@0.33.1':
+    resolution: {integrity: sha512-G7kvFCVsllnJdE+UXROgN33aWnXQ3Cg/og6iuAl9bVAPs0PhDUDWFAZVdXbTvBYHsoH9KzDuMdUnIq7G5EhXyg==}
+
+  '@guidepup/playwright@0.19.1':
+    resolution: {integrity: sha512-d0FMH6LFbRbV71l2NGzv2gqV3vQbHDfTVctXsKm6d1ZahpS2/Ozq1WCEoZ7QTAR6iuNzwy03tZfvyijGH+zUDw==}
+    peerDependencies:
+      '@guidepup/guidepup': '>=0.33.0'
+      '@playwright/test': ^1.57.0
+
+  '@guidepup/setup@0.24.6':
+    resolution: {integrity: sha512-Oxcb0aXTVhl0iXYYuecUjTU4Bt0P7+qsOktcLNSnhwdynBYesUofTfk9QdboOhqLmg5wesw4qE3hXDHCgCz5OA==}
+    hasBin: true
+
   '@html-validate/stylish@6.0.0':
     resolution: {integrity: sha512-d1/lI3qIXhGVJF3+MmKEBn1dRX6U4Z+BDaOdDI3E6SXcO+OQ7hC/3mSo6BIjwQlcuV6NdDOKm6QCrzIQL1EezQ==}
     engines: {node: ^22.16.0 || >= 24.0.0}
@@ -4340,6 +4363,10 @@ packages:
   '@wooorm/starry-night@3.10.0':
     resolution: {integrity: sha512-JRp2va6hfbC14fXgYQTmwdl4j1+4ZID9KKkCD+Mn/+B/j1QMlzZYPUtXOFNxA+CWrEo+IPha6EMVbsap2OFZig==}
 
+  '@xmldom/xmldom@0.9.11':
+    resolution: {integrity: sha512-tW8bcK3hsG0/uqSnNz6TK4BkcuZSezoU7DlnYssILmZDktPnSHHuDJJFM0AJv+13gz2r0iGdrj6qqKeUnxXEDg==}
+    engines: {node: '>=14.6'}
+
   '@xtuc/ieee754@1.2.0':
     resolution: {integrity: sha512-DX8nKgqcGwsc0eJSqYt5lwP4DH5FlHnmuWWBRy7X0NcaGR0ZtuyeESgMwTYVEtxmsNGY+qit4QYT/MIYTOTPeA==}
 
@@ -4672,6 +4699,9 @@ packages:
   bl@4.1.0:
     resolution: {integrity: sha512-1W07cM9gS6DcLperZfFSj+bWLtaPGSOHWhPiGzXmvVJbRLdG82sH/Kn8EtW1VqWVA54AKf2h5k5BbnIbwF3h6w==}
 
+  bluebird@3.7.2:
+    resolution: {integrity: sha512-XpNj6GDQzdfW+r2Wnn7xiSAd7TM3jzkxGXBGTtWKuSXv1xUV+azxAm8jdWZN06QTQk+2N2XB9jRDkvbmQmcRtg==}
+
   boolbase@1.0.0:
     resolution: {integrity: sha512-JZOSA7Mo9sNGB8+UjSgzdLtokWAky1zbztM3WRLCbZ70/3cTANmQmOdR7y2g+J0e2WXywy1yS468tY+IruqEww==}
 
@@ -4943,6 +4973,10 @@ packages:
     resolution: {integrity: sha512-y4Mg2tXshplEbSGzx7amzPwKKOCGuoSRP/CjEdwwk0FOGlUbq6lKuoyDZTNZkmxHdJtp54hdfY/JUrdL7Xfdug==}
     engines: {node: '>=14'}
 
+  commander@15.0.0:
+    resolution: {integrity: sha512-z67u4ZhzCL/Tydu1lJARtEZYWbWaN7oYLHbsuzocr6y4N6WZAagG3RQ4FW61V1/0+jImpj293XfrcYnd1qxtPg==}
+    engines: {node: '>=22.12.0'}
+
   commander@2.20.3:
     resolution: {integrity: sha512-GpVkmM8vF2vQUkj2LvZmD35JxeJOLCwJ9cUkugyk2nuhbv3+mJvpLYYt+0+USMxE+oj+ey/lJEnhZw75x/OMcQ==}
 
@@ -5008,6 +5042,7 @@ packages:
   conventional-changelog-core@5.0.1:
     resolution: {integrity: sha512-Rvi5pH+LvgsqGwZPZ3Cq/tz4ty7mjijhr3qR4m9IBXNbxGGYgTVVO+duXzz9aArmHxFtwZ+LRkrNIMDQzgoY4A==}
     engines: {node: '>=14'}
+    deprecated: Deprecated and no longer maintained. Please use conventional-changelog instead.
 
   conventional-changelog-preset-loader@3.0.0:
     resolution: {integrity: sha512-qy9XbdSLmVnwnvzEisjxdDiLA4OmV3o8db+Zdg4WiFw14fP3B6XNz98X0swPPpkTd/pc1K7+adKgEDM1JCUMiA==}
@@ -5287,6 +5322,9 @@ packages:
     resolution: {integrity: sha512-KIN/nDJBQRcXw0MLVhZE9iQHmG68qAVIBg9CqmUYjmQIhgij9U5MFvrqkUL5FbtyyzZuOeOt0zdeRe4UY7ct+A==}
     engines: {node: '>= 0.4'}
 
+  duplexer2@0.1.4:
+    resolution: {integrity: sha512-asLFVfWWtJ90ZyOUHMqk7/S2w2guQKxUI2itj3d92ADHhxUSbCMGi1f1cBcJ7xM1To+pE/Khbwo1yuNbMEPKeA==}
+
   eastasianwidth@0.2.0:
     resolution: {integrity: sha512-I88TYZWc9XiYHRQ4/3c5rjjfgkjhLyW2luGIheGERbNQ6OY7yTybanSpDXZa8y7VUP9YmDcYa+eyq4ca7iLqWA==}
 
@@ -5834,6 +5872,10 @@ packages:
   fs-constants@1.0.0:
     resolution: {integrity: sha512-y6OAwoSIf7FyjMIv94u+b5rdheZEjzR63GTyZJm5qh4Bi+2YgwLCcI/fPFZkL5PSixOt6ZNKm+w+Hfp/Bciwow==}
 
+  fs-extra@11.3.1:
+    resolution: {integrity: sha512-eXvGGwZ5CL17ZSwHWd3bbgk7UUpF6IFHtP57NYYakPvHOs8GDgDe5KJI36jIJzDkJ6eJjuzRA8eBQb6SkKue0g==}
+    engines: {node: '>=14.14'}
+
   fs-extra@11.3.4:
     resolution: {integrity: sha512-CTXd6rk/M3/ULNQj8FBqBWHYBVYybQ3VPBw0xGKFe3tuH7ytT6ACnvzpIQ3UZtB8yvUKC2cXn1a+x+5EVQLovA==}
     engines: {node: '>=14.14'}
@@ -7480,6 +7522,9 @@ packages:
   node-html-parser@9.0.0:
     resolution: {integrity: sha512-MhdaHPyxnyYu/sf0TpiRvDnTrkum0UKHC7FdbDGIUQNlx3I7xzwXoyV0eMUMv/XU+lkJT1glOUzpDPq7b2p1Ew==}
 
+  node-int64@0.4.0:
+    resolution: {integrity: sha512-O5lz91xSOeoXP6DulyHfllpq+Eg00MWitZIbtPfoSEvqIHdl5gfcY6hYzDWnj0qD5tz52PI08u9qUvSVeUBeHw==}
+
   node-releases@2.0.51:
     resolution: {integrity: sha512-wRNIrw4DmVLKQlbgOMdkMx27Wrpzes2hh5Jtbi2bjPd+4wJstWIqP5A+lscnqbm0xxmT5Bpg8Lec5ItEBwx6BQ==}
     engines: {node: '>=18'}
@@ -7918,6 +7963,10 @@ packages:
     engines: {node: '>=20'}
     hasBin: true
 
+  plist@4.0.0:
+    resolution: {integrity: sha512-4dOqNo0Y2NpfSf9q4+zr4bh7pzNWeckIam34Z0KYJhg8qtNNfh59VbD+Yna5SjwcxawVvLKx5w5FtuCijpEF4Q==}
+    engines: {node: '>=18'}
+
   pngjs@7.0.0:
     resolution: {integrity: sha512-LKWqWJRhstyYo9pGvgor/ivk2w94eSjE3RGVuzLGlr3NmD8bf7RcYGze1mNdEHRP6TRP6rMuDHk5t44hnTRyow==}
     engines: {node: '>=14.19.0'}
@@ -9116,6 +9165,10 @@ packages:
   undici-types@6.21.0:
     resolution: {integrity: sha512-iwDZqg0QAGrg9Rav5H4n0M64c3mkR59cJ6wQp+7C4nI0gsmExaedaYLNO44eT4AtBBwjbTiGPMlt2Md0T9H9JQ==}
 
+  undici@8.10.0:
+    resolution: {integrity: sha512-HvltHd7avK13QIw/oLe4qoOLyoVSoafqJ2jYOrtMRBkbYT31eiBQ8O0ehRKZiEZCMEyLFQNIADpgCWC5fALvYQ==}
+    engines: {node: '>=22.19.0'}
+
   unicode-canonical-property-names-ecmascript@2.0.1:
     resolution: {integrity: sha512-dA8WbNeb2a6oQzAQ55YlT5vQAWGV9WXOsi3SskE3bcCdM0P4SDd+24zS/OCacdRq5BkdsRj9q3Pg6YyQoxIGqg==}
     engines: {node: '>=4'}
@@ -9197,6 +9250,9 @@ packages:
   unrs-resolver@1.12.2:
     resolution: {integrity: sha512-dmlRxBJJayXjqTwC+JtF1HhJmgf3ftQ3YejFcZrf4+KKtJv0qDsK1pjqaaVjG7wJ5NJ6UVP1OqRMQ71Z4C3rxQ==}
 
+  unzipper@0.12.5:
+    resolution: {integrity: sha512-tXYOi9R57Uj/2Z25SOs5RRSzq886MBQj2gY8dPL+xl/kv6s6SvByoKfAtvfVeEuhntWDgjd2o9p2lb4TVPAz0A==}
+
   upath@2.0.1:
     resolution: {integrity: sha512-1uEe95xksV1O0CYKXo8vQvN1JEbtJp7lb7C5U9HMsIp6IVwntkH/oNUzyVNQSd4S1sYk2FpSSW44FqMc8qee5w==}
     engines: {node: '>=4'}
@@ -9550,6 +9606,10 @@ packages:
     resolution: {integrity: sha512-EvGK8EJ3DhaHfbRlETOWAS5pO9MZITeauHKJyb8wyajUfQUenkIg2MvLDTZ4T/TgIcm3HU0TFBgWWboAZ30UHg==}
     engines: {node: '>=18'}
 
+  xmlbuilder@15.1.1:
+    resolution: {integrity: sha512-yMqGBqtXyeN1e3TGYvgNgDVZ3j84W4cwkOXQswghol6APgZWaff9lnbvN7MHYJOiXsvGPXtjTYJEiC9J2wv9Eg==}
+    engines: {node: '>=8.0'}
+
   xmlchars@2.2.0:
     resolution: {integrity: sha512-JZnDKK8B0RCDw84FNdDAIpZK+JuJw+s7Lz8nksI7SIuU3UXJJslUthsi+uWBUYOwPFwW7W7PRLRfUKpxjtjFCw==}
 
@@ -10833,6 +10893,23 @@ snapshots:
 
   '@gar/promise-retry@1.0.3': {}
 
+  '@guidepup/guidepup@0.33.1':
+    dependencies:
+      plist: 4.0.0
+
+  '@guidepup/playwright@0.19.1(@guidepup/guidepup@0.33.1)(@playwright/test@1.62.1)':
+    dependencies:
+      '@guidepup/guidepup': 0.33.1
+      '@playwright/test': 1.62.1
+
+  '@guidepup/setup@0.24.6':
+    dependencies:
+      chalk: 4.1.2
+      commander: 15.0.0
+      semver: 7.8.5
+      undici: 8.10.0
+      unzipper: 0.12.5
+
   '@html-validate/stylish@6.0.0': {}
 
   '@humanfs/core@0.19.1': {}
@@ -11333,7 +11410,7 @@ snapshots:
       - tsx
       - yaml
 
-  '@mui/internal-code-infra@0.0.4-canary.101(4c6243aed1f3c8d993ccce0bc6817d78)':
+  '@mui/internal-code-infra@0.0.4-canary.101(4dd64b75bdb2e090bf30a93c72a30a32)':
     dependencies:
       '@argos-ci/core': 6.5.0(@types/node@22.20.1)(supports-color@7.2.0)
       '@babel/cli': 7.29.7(@babel/core@7.29.7(supports-color@7.2.0))
@@ -11381,7 +11458,7 @@ snapshots:
       eslint-plugin-compat: 7.0.2(eslint@10.8.1(jiti@2.7.0)(supports-color@7.2.0))
       eslint-plugin-import: 2.32.0(@typescript-eslint/parser@8.67.0(eslint@10.8.1(jiti@2.7.0)(supports-color@7.2.0))(supports-color@7.2.0)(typescript@6.0.3))(eslint-import-resolver-typescript@4.4.5)(eslint@10.8.1(jiti@2.7.0)(supports-color@7.2.0))(supports-color@7.2.0)
       eslint-plugin-jsx-a11y: 6.10.2(eslint@10.8.1(jiti@2.7.0)(supports-color@7.2.0))
-      eslint-plugin-mdx: 3.8.1(eslint@10.8.1(jiti@2.7.0)(supports-color@7.2.0))(supports-color@7.2.0)
+      eslint-plugin-mdx: 3.8.1(bluebird@3.7.2)(eslint@10.8.1(jiti@2.7.0)(supports-color@7.2.0))(supports-color@7.2.0)
       eslint-plugin-mocha: 11.3.0(eslint@10.8.1(jiti@2.7.0)(supports-color@7.2.0))
       eslint-plugin-react: 7.37.5(eslint@10.8.1(jiti@2.7.0)(supports-color@7.2.0))
       eslint-plugin-react-compiler: 19.1.0-rc.2(eslint@10.8.1(jiti@2.7.0)(supports-color@7.2.0))(supports-color@7.2.0)
@@ -11766,10 +11843,10 @@ snapshots:
     transitivePeerDependencies:
       - supports-color
 
-  '@npmcli/config@8.3.4':
+  '@npmcli/config@8.3.4(bluebird@3.7.2)':
     dependencies:
       '@npmcli/map-workspaces': 3.0.6
-      '@npmcli/package-json': 5.2.1
+      '@npmcli/package-json': 5.2.1(bluebird@3.7.2)
       ci-info: 4.3.1
       ini: 4.1.3
       nopt: 7.2.1
@@ -11787,14 +11864,14 @@ snapshots:
     dependencies:
       semver: 7.8.5
 
-  '@npmcli/git@5.0.8':
+  '@npmcli/git@5.0.8(bluebird@3.7.2)':
     dependencies:
       '@npmcli/promise-spawn': 7.0.2
       ini: 4.1.3
       lru-cache: 10.4.3
       npm-pick-manifest: 9.1.0
       proc-log: 4.2.0
-      promise-inflight: 1.0.1
+      promise-inflight: 1.0.1(bluebird@3.7.2)
       promise-retry: 2.0.1
       semver: 7.8.5
       which: 4.0.0
@@ -11867,9 +11944,9 @@ snapshots:
 
   '@npmcli/node-gyp@5.0.0': {}
 
-  '@npmcli/package-json@5.2.1':
+  '@npmcli/package-json@5.2.1(bluebird@3.7.2)':
     dependencies:
-      '@npmcli/git': 5.0.8
+      '@npmcli/git': 5.0.8(bluebird@3.7.2)
       glob: 10.5.0
       hosted-git-info: 7.0.2
       json-parse-even-better-errors: 3.0.2
@@ -13816,6 +13893,8 @@ snapshots:
       vscode-oniguruma: 2.0.1
       vscode-textmate: 9.3.2
 
+  '@xmldom/xmldom@0.9.11': {}
+
   '@xtuc/ieee754@1.2.0': {}
 
   '@xtuc/long@4.2.2': {}
@@ -14162,6 +14241,8 @@ snapshots:
       inherits: 2.0.4
       readable-stream: 3.6.2
 
+  bluebird@3.7.2: {}
+
   boolbase@1.0.0: {}
 
   boxen@7.0.0:
@@ -14435,6 +14516,8 @@ snapshots:
 
   commander@10.0.1: {}
 
+  commander@15.0.0: {}
+
   commander@2.20.3: {}
 
   commander@4.1.1: {}
@@ -14804,6 +14887,10 @@ snapshots:
       es-errors: 1.3.0
       gopd: 1.2.0
 
+  duplexer2@0.1.4:
+    dependencies:
+      readable-stream: 2.3.8
+
   eastasianwidth@0.2.0: {}
 
   ejs@3.1.10:
@@ -15059,7 +15146,7 @@ snapshots:
     transitivePeerDependencies:
       - supports-color
 
-  eslint-mdx@3.8.1(eslint@10.8.1(jiti@2.7.0)(supports-color@7.2.0))(supports-color@7.2.0):
+  eslint-mdx@3.8.1(bluebird@3.7.2)(eslint@10.8.1(jiti@2.7.0)(supports-color@7.2.0))(supports-color@7.2.0):
     dependencies:
       acorn: 8.16.0
       acorn-jsx: 5.3.2(acorn@8.16.0)
@@ -15071,7 +15158,7 @@ snapshots:
       remark-stringify: 11.0.0
       synckit: 0.11.12
       unified: 11.0.5
-      unified-engine: 11.2.2(supports-color@7.2.0)
+      unified-engine: 11.2.2(bluebird@3.7.2)(supports-color@7.2.0)
       unist-util-visit: 5.1.0
       vfile: 6.0.3
     transitivePeerDependencies:
@@ -15168,10 +15255,10 @@ snapshots:
       safe-regex-test: 1.1.0
       string.prototype.includes: 2.0.1
 
-  eslint-plugin-mdx@3.8.1(eslint@10.8.1(jiti@2.7.0)(supports-color@7.2.0))(supports-color@7.2.0):
+  eslint-plugin-mdx@3.8.1(bluebird@3.7.2)(eslint@10.8.1(jiti@2.7.0)(supports-color@7.2.0))(supports-color@7.2.0):
     dependencies:
       eslint: 10.8.1(jiti@2.7.0)(supports-color@7.2.0)
-      eslint-mdx: 3.8.1(eslint@10.8.1(jiti@2.7.0)(supports-color@7.2.0))(supports-color@7.2.0)
+      eslint-mdx: 3.8.1(bluebird@3.7.2)(eslint@10.8.1(jiti@2.7.0)(supports-color@7.2.0))(supports-color@7.2.0)
       mdast-util-from-markdown: 2.0.3(supports-color@7.2.0)
       mdast-util-mdx: 3.0.0(supports-color@7.2.0)
       micromark-extension-mdxjs: 3.0.0
@@ -15620,6 +15707,12 @@ snapshots:
 
   fs-constants@1.0.0: {}
 
+  fs-extra@11.3.1:
+    dependencies:
+      graceful-fs: 4.2.11
+      jsonfile: 6.2.0
+      universalify: 2.0.1
+
   fs-extra@11.3.4:
     dependencies:
       graceful-fs: 4.2.11
@@ -16762,9 +16855,9 @@ snapshots:
       strip-bom: 4.0.0
       type-fest: 0.6.0
 
-  load-plugin@6.0.3:
+  load-plugin@6.0.3(bluebird@3.7.2):
     dependencies:
-      '@npmcli/config': 8.3.4
+      '@npmcli/config': 8.3.4(bluebird@3.7.2)
       import-meta-resolve: 4.2.0
     transitivePeerDependencies:
       - bluebird
@@ -17761,6 +17854,8 @@ snapshots:
       css-select: 5.2.2
       entities: 8.0.0
 
+  node-int64@0.4.0: {}
+
   node-releases@2.0.51: {}
 
   nopt@7.2.1:
@@ -18375,6 +18470,11 @@ snapshots:
     optionalDependencies:
       fsevents: 2.3.2
 
+  plist@4.0.0:
+    dependencies:
+      '@xmldom/xmldom': 0.9.11
+      xmlbuilder: 15.1.1
+
   pngjs@7.0.0: {}
 
   possible-typed-array-names@1.1.0: {}
@@ -18486,7 +18586,9 @@ snapshots:
 
   promise-call-limit@3.0.2: {}
 
-  promise-inflight@1.0.1: {}
+  promise-inflight@1.0.1(bluebird@3.7.2):
+    optionalDependencies:
+      bluebird: 3.7.2
 
   promise-retry@2.0.1:
     dependencies:
@@ -19923,6 +20025,8 @@ snapshots:
 
   undici-types@6.21.0: {}
 
+  undici@8.10.0: {}
+
   unicode-canonical-property-names-ecmascript@2.0.1: {}
 
   unicode-emoji-modifier-base@1.0.0: {}
@@ -19940,7 +20044,7 @@ snapshots:
 
   unicorn-magic@0.4.0: {}
 
-  unified-engine@11.2.2(supports-color@7.2.0):
+  unified-engine@11.2.2(bluebird@3.7.2)(supports-color@7.2.0):
     dependencies:
       '@types/concat-stream': 2.0.3
       '@types/debug': 4.1.13
@@ -19954,7 +20058,7 @@ snapshots:
       ignore: 6.0.2
       is-empty: 1.2.0
       is-plain-obj: 4.1.0
-      load-plugin: 6.0.3
+      load-plugin: 6.0.3(bluebird@3.7.2)
       parse-json: 7.1.1
       trough: 2.2.0
       unist-util-inspect: 8.1.0
@@ -20068,6 +20172,14 @@ snapshots:
       '@unrs/resolver-binding-win32-ia32-msvc': 1.12.2
       '@unrs/resolver-binding-win32-x64-msvc': 1.12.2
 
+  unzipper@0.12.5:
+    dependencies:
+      bluebird: 3.7.2
+      duplexer2: 0.1.4
+      fs-extra: 11.3.1
+      graceful-fs: 4.2.11
+      node-int64: 0.4.0
+
   upath@2.0.1: {}
 
   update-browserslist-db@1.2.3(browserslist@4.28.6):
@@ -20455,6 +20567,8 @@ snapshots:
 
   xml-name-validator@5.0.0: {}
 
+  xmlbuilder@15.1.1: {}
+
   xmlchars@2.2.0: {}
 
   xtend@4.0.2: {}
diff --git a/pnpm-workspace.yaml b/pnpm-workspace.yaml
index bb160b82760..78396c221cc 100644
--- a/pnpm-workspace.yaml
+++ b/pnpm-workspace.yaml
@@ -24,6 +24,8 @@ allowBuilds:
 #
 # Remove each entry once the parent dependency ships the fixed version on its own.
 overrides:
+  # Screen recording is not needed for the tests and pulls in ffmpeg-static.
+  '@guidepup/setup>@guidepup/record': '-'
   # via lerna -> minimatch, eslint-plugin-* -> minimatch (GHSA-3jxr-9vmj-r5cp)
   brace-expansion@1: '1.1.18'
   brace-expansion@2: '2.1.4'
@@ -53,7 +55,6 @@ overrides:
   tar: '^7.5.22'
   # via @vitest/browser (GHSA-96hv-2xvq-fx4p)
   ws: '^8.21.3'
-
 engineStrict: true
 updateNotifier: false
 blockExoticSubdeps: true
diff --git a/test/README.md b/test/README.md
index 7b6aadb6a7e..3356447c5e3 100644
--- a/test/README.md
+++ b/test/README.md
@@ -171,6 +171,33 @@ Check out the [visual regression testing readme](./regressions/README.md) for mo
 
 Checkout the [end-to-end testing readme](./e2e/README.md) for more information.
 
+#### Screen reader tests
+
+Screen reader tests use [Guidepup](https://www.guidepup.dev/) with the existing end-to-end
+fixtures. They run in a headed Chromium browser with VoiceOver on macOS or NVDA on Windows.
+The screen reader must use English because the tests and Guidepup's navigation match English
+announcements.
+
+The setup package is installed by `pnpm install`. On macOS, developers who run these tests must
+configure their host once:
+
+```bash
+pnpm test:screen-reader:setup
+```
+
+This macOS-level step is intentionally not run during `pnpm install` because it changes system
+settings and may require manual permission prompts.
+
+If the test fails with `Failed to mount Guidepup preferences` and an `EPERM` error, grant Full
+Disk Access to the terminal, IDE, or other application running the test under **System Settings
+→ Privacy & Security → Full Disk Access**. Fully quit and reopen that application before retrying.
+
+Then run `pnpm test:screen-reader`. The compatible screen reader assets are installed
+automatically before the test.
+
+GitHub Actions runs the same cross-platform test with NVDA and Chrome on a Windows Server 2025
+runner.
+
 ##### Development
 
 When working on the visual regression tests you can run `pnpm test:regressions:dev` in the background to constantly rebuild the views used for visual regression testing.
diff --git a/test/screen-reader/playwright.config.ts b/test/screen-reader/playwright.config.ts
new file mode 100644
index 00000000000..1678fdac0e6
--- /dev/null
+++ b/test/screen-reader/playwright.config.ts
@@ -0,0 +1,33 @@
+import { defineConfig, devices } from '@playwright/test';
+import { screenReaderConfig } from '@guidepup/playwright';
+
+const BASE_URL = 'http://localhost:5173';
+
+export default defineConfig({
+  ...screenReaderConfig,
+  outputDir: '../../test-results/screen-reader',
+  testDir: '.',
+  testMatch: '*.spec.ts',
+  timeout: 5 * 60_000,
+  retries: 1,
+  use: {
+    ...screenReaderConfig.use,
+    baseURL: BASE_URL,
+  },
+  projects: [
+    {
+      name: 'chromium',
+      use: {
+        ...devices['Desktop Chrome'],
+        channel: process.env.CI ? 'chrome' : undefined,
+      },
+    },
+  ],
+  webServer: {
+    command: 'pnpm test:e2e:dev',
+    cwd: process.cwd(),
+    reuseExistingServer: !process.env.CI,
+    timeout: 120_000,
+    url: BASE_URL,
+  },
+});
diff --git a/test/screen-reader/radio.spec.ts b/test/screen-reader/radio.spec.ts
new file mode 100644
index 00000000000..a1b6450183a
--- /dev/null
+++ b/test/screen-reader/radio.spec.ts
@@ -0,0 +1,38 @@
+import { expect } from '@playwright/test';
+import { screenReaderTest as test, type ScreenReaderPlaywright } from '@guidepup/playwright';
+
+const MAX_NAVIGATION_STEPS = 10;
+
+async function navigateToItem(
+  screenReader: ScreenReaderPlaywright,
+  name: RegExp,
+  step = 0,
+): Promise<string> {
+  const itemText = await screenReader.itemText();
+
+  if (name.test(itemText)) {
+    return itemText;
+  }
+
+  if (step === MAX_NAVIGATION_STEPS) {
+    throw new Error(`Guidepup did not navigate to an item matching ${name}.`);
+  }
+
+  await screenReader.next();
+  return navigateToItem(screenReader, name, step + 1);
+}
+
+test.use({ screenReaderStartOptions: { capture: true } });
+
+test("announces a radio option's accessible name", async ({ page, screenReader }) => {
+  await page.goto('/e2e-fixtures/Radio#no-dev');
+  await page.locator('[data-testid="testcase"]:not([aria-busy="true"])').waitFor();
+  await screenReader.navigateToWebContent();
+
+  const itemText = await navigateToItem(screenReader, /fuji/i);
+  const spokenPhrase = await screenReader.lastSpokenPhrase();
+
+  expect(itemText).toMatch(/fuji/i);
+  expect(spokenPhrase).toMatch(/fuji/i);
+  expect(spokenPhrase).toMatch(/radio/i);
+});
diff --git a/test/tsconfig.json b/test/tsconfig.json
index 7fbdf4b4fea..365cc7f54c2 100644
--- a/test/tsconfig.json
+++ b/test/tsconfig.json
@@ -5,6 +5,6 @@
     "moduleResolution": "bundler",
     "types": ["vite/client", "vitest/globals", "@testing-library/jest-dom"]
   },
-  "include": ["e2e/**/*", "regressions/**/*", "./*.ts"],
+  "include": ["e2e/**/*", "regressions/**/*", "screen-reader/**/*", "./*.ts"],
   "exclude": ["node_modules", "build"]
 }