diff --git a/src/build/virtual/app.ts b/src/build/virtual/app.ts
index a1500ab6c1..55578eda3d 100644
--- a/src/build/virtual/app.ts
+++ b/src/build/virtual/app.ts
@@ -11,6 +11,7 @@ export default function app(nitro: Nitro) {
       const hasPlugins = nitro.options.plugins.length > 0;
       const hasHooks = nitro.options.features?.runtimeHooks ?? hasPlugins;
       const hasAsyncContext = !!nitro.options.experimental.asyncContext;
+      const runtimeBaseUrl = nitro.options.features.runtimeBaseURL;
 
       const routingImports = [
         hasRoutes && "findRoute",
@@ -90,6 +91,18 @@ export default function app(nitro: Nitro) {
         `  };`
       );
 
+      if (runtimeBaseUrl) {
+        imports.push(`import { requestWithBaseURL } from "h3";`);
+        code.push(
+          ``,
+          `  const baseUrl = process.env.NITRO_APP_BASE_URL ?? "";`,
+          `  const baseHandler = appHandler;`,
+          `  appHandler = (req) => {`,
+          `    return baseHandler(requestWithBaseURL(req, baseUrl));`,
+          `  };`
+        );
+      }
+
       if (hasAsyncContext) {
         imports.push(`import { nitroAsyncContext } from "#nitro/runtime/context";`);
         code.push(
diff --git a/src/types/config.ts b/src/types/config.ts
index f7cb88d810..83ba1443ce 100644
--- a/src/types/config.ts
+++ b/src/types/config.ts
@@ -314,6 +314,11 @@ export interface NitroOptions extends PresetOptions {
      * Enable WebSocket support.
      */
     websocket?: boolean;
+
+    /**
+     * Enable NITRO_APP_BASE_URL env var to take effect at runtime
+     */
+    runtimeBaseURL?: boolean;
   };
 
   /**
diff --git a/src/types/global.ts b/src/types/global.ts
index 3af8907827..dc8d4fd2cf 100644
--- a/src/types/global.ts
+++ b/src/types/global.ts
@@ -12,6 +12,7 @@ export interface NitroImportMeta {
   _asyncContext?: boolean;
   _tasks?: boolean;
   _websocket?: boolean;
+  _runtimeBaseURL?: boolean;
 }
 
 declare global {