Exception: An error occurred while calling MHCnuggets:
/usr/local/lib/python3.10/dist-packages/keras/src/layers/core/masking.py:47: UserWarning: Do not pass an `input_shape`/`input_dim` argument to a layer. When using Sequential models, prefer using an `Input(shape)` object as the first layer in the model instead.
super().__init__(**kwargs)
Traceback (most recent call last):
File "/usr/local/lib/python3.10/dist-packages/pvactools/lib/call_mhcnuggets.py", line 84, in <module>
main()
File "/usr/local/lib/python3.10/dist-packages/pvactools/lib/call_mhcnuggets.py", line 61, in main
predict(args.class_type, tmp_file.name, mhcnuggets_allele(args.allele, args.class_type), output=tmp_output_file.name, rank_output=True)
File "/usr/local/lib/python3.10/dist-packages/mhcnuggets/src/predict.py", line 93, in predict
model.compile(loss='mse', optimizer=Adam(lr=0.001))
File "/usr/local/lib/python3.10/dist-packages/keras/src/optimizers/adam.py", line 60, in __init__
super().__init__(
File "/usr/local/lib/python3.10/dist-packages/keras/src/backend/tensorflow/optimizer.py", line 19, in __init__
super().__init__(*args, **kwargs)
File "/usr/local/lib/python3.10/dist-packages/keras/src/optimizers/base_optimizer.py", line 38, in __init__
raise ValueError(f"Argument(s) not recognized: {kwargs}")
ValueError: Argument(s) not recognized: {'lr': 0.001}
Hello, as you can see in pVACtools issue griffithlab/pVACtools#1084 - https://github.com/openvax/mhcflurry and mhcnuggets doesn't work with latest 2.16.1 version of tensorflow.
Looks like some legacy code stopped working:
https://github.com/KarchinLab/mhcnuggets/blob/master/mhcnuggets/src/predict.py#L90-L93
Maybe tensorflow version should be pinned until code is fixed?
Similar openvax/mhcflurry#234 issue.